When coronary heart disease shows symptoms, they usually manifest themselves in the form of chest pain. If patients take these signs of angina pectoris seriously and present themselves to their physicians, non-invasive examinations such as blood tests, echocardiography and, above all, electrocardiography (ECG) are usually carried out first, as recommended in international medical guidelines , . In more than two thirds of these cases, the ECG is the first step in the medical diagnosis . This allows a quick examination of the patient without having to expose him or her directly to radiation or invasive procedures.
Unfortunately, this „absence of side effects“ of the ECG is associated with limited diagnostic accuracy, as shown by corresponding studies: The sensitivity of electrocardiography usually fluctuates within a range of 50 ± 15%, which is why patients with chest pain are often discharged without good reason [6-12].
The central role of the heart muscle for the human body is not a new insight. This fact usually becomes most obvious when it comes to the consequences of dysfunctions and their frequency. More than every third US citizen suffers from at least one form of cardiovascular disease. The American Heart Association (AHA) also estimates that this figure will rise to around 44 % of the total population by 2030. This makes cardiovascular diseases the leading cause of death in the United States since 1919. Of these, coronary heart disease (CHD) is the main killer, accounting for 45% of all annual deaths . In Europe, too, the heart is the organ with the most fatal disease cases. Here, CHD, also known as ischemic heart disease, is the leading cause of death with 119 deaths per 100,000 inhabitants .